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Updated: Jan 23, 2026

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肝臓のグルコースは,CREBの共活性化器CRTC2を介して検出されます

Renaud Dentin1, Susan Hedrick, Jianxin Xie

  • 1Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|March 8, 2008
PubMed
まとめ

高レベルのグルコースは,ヘクソサミン生物合成経路 (HBP) を活性化し,タンパク質O-グリコシル化につながります. O-GlcNAcaseによって媒介されるこのプロセスは,グルコース不耐症と糖尿病の合併症に不可欠です.

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