CrtamによるT細胞の極性およびエフェクタ機能の遅い段階の調節

Jung-Hua Yeh1, Sachdev S Sidhu, Andrew C Chan

  • 1Department of Immunology, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.

Cell
|March 11, 2008
PubMed
まとめ

クラスIのMHC受限型T細胞関連分子 (Crtam) は,T細胞の遅い極性を確立し,CD4+T細胞におけるIFNgammaとIL22の産生を促進する. このダイナミックな調節は,初期活性化から数時間後に適応性免疫反応に影響を与える.

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