この患者さんは,細菌性腹膜炎や門脈高血圧を患っていますか? パラセンテシスを実行し,結果を分析するにはどうすればよいですか?
Camilla L Wong1, Jayna Holroyd-Leduc, Kevin E Thorpe
1Division of Geriatric Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
JAMA
|March 13, 2008
まとめ
血液培養ボトルにアシチス液をベッドサイドで注射することで,診断結果が改善されます. 特定のアシチス液のパラメータは,自発的な細菌性腹膜炎とポータル高血圧の診断に役立ちます.
科学分野:
- 胃腸内科 胃腸内科
- 肝臓病理学 肝臓病理学
- 内科内科は,内科の内科である.
背景:
- 腹部のパラセンテシスは,アシテスの管理のための一般的な手順です.
- インダクションには,感染の評価,ポータル高血圧の評価,耐火性アシテスの治療が含まれます.
研究 の 目的:
- 副作用を減らすためにパラセンテシス技術に関する証拠を体系的に検討する.
- 診断成果を改善するための方法を評価する.
- spontaneous bacterial peritonitisとポータル高血圧の診断のためのアスキティック液体分析の精度を決定する.
主な方法:
- メドラインとEMBASE (1966-2007) の英語研究の体系的なレビュー.
- パラセンテシスの介入 (凝固,針のタイプ,超音波,ベッドサイドの予防接種,プラズマ拡張器) に関する研究が含まれています.
- 自発的な細菌性腹膜炎とポータル高血圧の診断のためのアシチス液の生化学分析に関する研究が含まれています.
主要な成果:
- 処置前の凝固検査は不要である可能性が高い.
- 15ゲージの針カヌラは,14ゲージの針と比較して合併症を減らすことができます.
- 培養ボトルをベッドサイドで即座に接種することで,診断収量が大幅に改善されます.
- アシチス液の多形態核白血球 (PMN) 数>250細胞/μL,白血球数>1000細胞/μL,pH <7.35,または血液-アシチス液のpHグラデント ≥0.10は,自発的な細菌性膜炎の可能性を高めます.
- 血清アシテスアルブミン梯度<1.1g/dLは,ポータル高血圧の可能性を低下させる.
結論:
- 血液培養ボトルにアシチス液のベッドサイド注射が推奨されます.
- 特定のアシチス液のパラメータは,自発的な細菌性膜炎の診断に役立ちます.
- 血清アシテスアルブミングラデントは,ポータル高血圧の評価に価値があります.
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