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Updated: Jul 27, 2026

Focus Formation: A Cell-based Assay to Determine the Oncogenic Potential of a Gene
08:18

Focus Formation: A Cell-based Assay to Determine the Oncogenic Potential of a Gene

Published on: December 31, 2014

ミトゲンシグナル伝達に障害がある変異したCSF-1受容体のMyc救出

M F Roussel1, J L Cleveland, S A Shurtleff

  • 1Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105.

Nature
|September 26, 1991
PubMed
まとめ

コロニー刺激因子-1受容体 (CSF-1R) のシグナル伝達経路は,チロシン809がc-myc誘導と細胞増殖に不可欠であることから,二分化します. これは,CSF-1主導の細胞成長におけるc-mycの中心的な役割を強調しています.

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