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Updated: Jul 6, 2026

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
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Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy

Published on: September 17, 2017

HET-s (((218-289) プリオンのアミロイド繊維は,三角形の水嫌性核を持つベータソレノイドを形成する

Christian Wasmer1, Adam Lange, Hélène Van Melckebeke

  • 1Physical Chemistry, ETH Zurich, 8093 Zurich, Switzerland.

Science (New York, N.Y.)
|March 15, 2008
PubMed
まとめ

研究者は,HET-sタンパク質を使用して,感染性のプリオン構造をモデル化しました. この原子解像度のモデルは,プリオン病の理解に不可欠な左利きベータソレノイド構造を明らかにしています.

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