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Updated: Feb 7, 2026

GPI Anchoring of Proteins in the ER Membrane
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腫瘍の維持は,eNOSによって媒介されます

Kian-Huat Lim1, Brooke B Ancrile, David F Kashatus

  • 1Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

Nature
|March 18, 2008
PubMed
まとめ

内皮酸化窒素合成酵素 (eNOS) のリン酸化を阻害すると,PI3K-AKT-eNOS経路を阻害することで腫瘍の成長を抑制する. この経路は,腫瘍性Rasの活性化を維持するために不可欠であり,腫瘍の発症と進行に不可欠です.

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