関連する実験動画

Updated: Jul 6, 2026

An In Vitro Assay to Detect tRNA-Isopentenyl Transferase Activity
07:46

An In Vitro Assay to Detect tRNA-Isopentenyl Transferase Activity

Published on: October 8, 2018

II型イソペンテニルジホスファートイソメラーゼ:フラビンの共性変異による不可逆的な不活性化

Steven C Rothman1, Jonathan B Johnston, Sungwon Lee

  • 1Department of Chemistry, University of Utah, Salt Lake City, Utah 84112, USA.

Journal of the American Chemical Society
|March 19, 2008
PubMed
まとめ

II型イソペンテニルジホスファートイソメラーゼ (IDI-2) は,減少したフラビンを使用し,フラビンのコファクターをアルキル化する基質アナログによって無活性化されます. これらの阻害剤は,IDI-2触媒のプロトネーション-デプロトネーションメカニズムを示唆しています.

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