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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

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単一の残留スイッチを使ったディターペン合成酵素反応の複雑性が高まっている

Dana Morrone1, Meimei Xu, D Bruce Fulton

  • 1Iowa State University, Department of Biochemistry, Biophysics, and Molecular Biology, Ames, Iowa 50011, USA.

Journal of the American Chemical Society
|March 28, 2008
PubMed
まとめ

テルペン合成酵素の単一のアミノ酸を変化させると,その反応の複雑性が劇的に変化します. この研究は,特定の残留物の置換が製品の結果を変えて,テルペノイドの天然製品の多様性に影響を与える方法を明らかにしています.

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