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Updated: Jul 6, 2026

Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo
10:24

Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo

Published on: May 9, 2016

コラーゲンのトリプルヘリックス安定性に対するトランスロックされたGly-Proアルケンのイソステルの効果

Nan Dai1, Xiaodong J Wang, Felicia A Etzkorn

  • 1Department of Chemistry, Virginia Tech, Blacksburg, Virginia 24061-0212, USA.

Journal of the American Chemical Society
|March 28, 2008
PubMed
まとめ

プロリンアミド結合をロックするためにGly-trans-Proアルケンのイソステルを合成すると,予期せぬ形でコラーゲンペプチドが不安定化します. この発見は,コラーゲンのトリプルヘリックス安定性とプロリンアミド結合ダイナミクスを超えた折り畳みに複雑な要因が影響することを示唆しています.

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Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides

Published on: January 31, 2014

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