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Updated: Apr 30, 2026

Murine Heterotopic Heart Transplant Technique
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白血球インテグリンMac-1は,急性心臓アロ移植拒絶を促進する

Koichi Shimizu1, Peter Libby, Rica Shubiki

  • 1Donald W. Reynolds Cardiovascular Clinical Research Center, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02115, USA. ksmz@rics.bwh.harvard.edu

Circulation
|April 2, 2008
PubMed
まとめ

受信者のMac-1欠乏症は,白血球の蓄積を減少させ,マクロファージの機能を改善することにより,心臓アロ移植の生存期間を大幅に延長しました. これは,アロインプラントの拒絶を防ぐための潜在的な治療目標としてMac-1を強調しています.

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