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Updated: May 2, 2026

Investigating Mast Cell Secretory Granules; from Biosynthesis to Exocytosis
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Published on: January 26, 2015

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Rab5の活性に関するイメージングは,ファゴソームの成熟のための重要なレギュレータを特定します

Masahiro Kitano1, Michio Nakaya, Takeshi Nakamura

  • 1Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Yoshida Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

Nature
|April 4, 2008
PubMed
まとめ

効率的なファゴサイトーシスは,初期のエンドソームの重要な調節体であるRab5に依存しています. この研究は,アポプトシス細胞の包み込み中にRab5の活性化ダイナミクスを明らかにし,ファゴソームの成熟におけるその役割を強調し,微小管に依存するグアニンヌクレオチド交換因子Gapex-5と関連付けました.

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