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Updated: Jul 5, 2026

Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method
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ケトステロイドイソメラーゼによる酵素強化結合運動/量子力学水素トンネリングの実験的証拠

Thomas C Wilde1, Grzegorz Blotny, Ralph M Pollack

  • 1Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland 21250, USA.

Journal of the American Chemical Society
|April 23, 2008
PubMed
まとめ

この研究では,酵素および非酵素反応における量子力学的水素トンネリング (HT) を調査した. 結果は,3-オクソ-デルタ(5) -ステロイドイソメラーゼ (KSI) がHTを強化し,その触媒速度加速に貢献することを示しています.

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