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Updated: May 19, 2026

A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters
07:47

A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters

Published on: April 20, 2015

Cl-/H+アンチポーターClC-7は,リゾソームにおける主要な塩化物浸透経路である

Austin R Graves1, Patricia K Curran, Carolyn L Smith

  • 1Membrane Transport Biophysics Unit, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 35 Convent Drive, Building 35, MSC 3701, Bethesda, Maryland 20892, USA.

Nature
|May 2, 2008
PubMed
まとめ

クロリドチャネル7 (ClC-7) は,重要なCl-/H+アンチポーターとして機能し,リソソーム酸性化を促進する. この研究は,細胞の分解と機能に不可欠なライソソームの主要なアニオントランスポーターとしてClC-7を特定しています.

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