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Updated: May 5, 2026

In vivo and in vitro Studies of Adaptor-clathrin Interaction
17:14

In vivo and in vitro Studies of Adaptor-clathrin Interaction

Published on: January 27, 2011

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エンドソーマのタンパク質Appl1は,脊椎動物の発達におけるAkt基板特異性と細胞生存を媒介する

Annette Schenck1, Livia Goto-Silva, Claudio Collinet

  • 1Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany.

Cell
|May 6, 2008
PubMed
まとめ

エンドソームタンパク質Appl1は,Aktの活性を調節することによって,ゼブラフィッシュの発達における細胞シグナル伝達特異性を制御する. この局所化は,特定のシグナル伝達経路をエンドソームに誘導することによって,適切な細胞生存を保証する.

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