アクティブキナーゼとキナーゼ欠乏キノームコレクションの適用は,ヘッジホッグのシグナル伝達を調節するキナーゼの識別のために

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Updated: Jul 5, 2026

Identification of Kinase-substrate Pairs Using High Throughput Screening
11:13

Identification of Kinase-substrate Pairs Using High Throughput Screening

Published on: August 29, 2015

Markku Varjosalo1, Mikael Björklund, Fang Cheng

  • 1Department of Molecular Medicine, National Public Health Institute (KTL), FI00290 Helsinki, Finland.

Cell
|May 6, 2008
PubMed
まとめ

この研究では,細胞シグナリングを調節する遺伝子を特定するために,キノム発現スクリーニング方法を開発しました. 研究者らは,ヘッジホッグ経路に関与するDYRK2やMAP3K10のような新しい調節物質を発見した.

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Quantitative PCR-based Assay to Measure Sonic Hedgehog Signaling in Cellular Model of Ciliogenesis07:26

Quantitative PCR-based Assay to Measure Sonic Hedgehog Signaling in Cellular Model of Ciliogenesis

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