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Updated: Jul 5, 2026

In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines
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In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines

Published on: May 12, 2023

アクリジン製薬によるDNA四重複認識の構造的基礎

Nancy H Campbell1, Gary N Parkinson, Anthony P Reszka

  • 1Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom.

Journal of the American Chemical Society
|May 7, 2008
PubMed
まとめ

研究者らは,抗癌薬BRACO-19でヒトのテロメア四重体の結晶構造を決定した. この薬は2つの四重複体の接点に結合し,新しいがんと戦うリガンドを設計するための洞察を提供します.

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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

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