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Updated: May 5, 2026

Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice
07:51

Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice

Published on: January 13, 2012

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トルセトラピブは,アトールバスタチン以上の動脈硬化症を軽減せず,アトールバスタチンよりも多くの炎症性病変を引き起こす

Willeke de Haan1, Jitske de Vries-van der Weij, José W A van der Hoorn

  • 1Leiden University Medical Center, Department of General Internal Medicine, Endocrinology, and Metabolic Diseases, 2300 RC Leiden, The Netherlands.

Circulation
|May 7, 2008
PubMed
まとめ

トルセトラピブによるコレステロールエステル転移タンパク質 (CETP) 阻害は,動脈硬化症を軽減したが,アトルバスタチンによる改善は認められなかった. トルセトラピブはまた,より不安定なプラークフェノタイプを促進し,炎症を増加させた.

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