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Updated: Jul 5, 2026

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

次世代のヘアピンポリアミドには (R) -3,4-アミノバター酸のターンユニットがあります

Christian Dose1, Michelle E Farkas, David M Chenoweth

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

Journal of the American Chemical Society
|May 8, 2008
PubMed
まとめ

研究者らは,ベータ-アミノ-ガンマ-ターンユニットを用いて新しいピロール-イミダゾールヘアピンポリアミドを開発した. これらの分子は,強化されたDNA結合を示し,遺伝子発現を抑制することができ,治療応用の可能性を示しています.

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Methionine Functionalized Biocompatible Block Copolymers for Targeted Plasmid DNA Delivery

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Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
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Copolymers are the products obtained from the polymerization of multiple monomer species. So, in a polymer chain itself, there can be multiple repeating units that come from different monomers. The process of synthesizing a polymer from different monomer species is called copolymerization. When two monomers are involved, the polymer is known as a bipolymer. Polymers with three and four monomers are termed terpolymers and quaterpolymers, respectively. Figure 1 depicts the copolymerization of...
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