INHはMPFの負の調節体であり,タンパク質フォスファターゼ2Aの一種である

T H Lee1, M J Solomon, M C Mumby

  • 1Department of Biochemistry and Biophysics, University of California, San Francisco 94143-0448.

Cell
|January 25, 1991
PubMed
まとめ

成熟促進因子 (MPF) は,細胞サイクル進行を推進する. この研究は,INHをタンパク質フォスファタゼ2Aとして特定し,MPFを鍵となるサブユニットを脱リン酸化することによって無活性化させ,細胞サイクル活性化に反対する.

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