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Updated: Jul 5, 2026

Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains
09:27

Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains

Published on: January 5, 2016

銅 ((II) は,パーキンソン病のタンパク質であるアルファ-シヌクレインに結合する

Jennifer C Lee1, Harry B Gray, Jay R Winkler

  • 1Laboratory of Molecular Biophysics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-8013, USA. leej4@mail.nih.gov

Journal of the American Chemical Society
|May 10, 2008
PubMed
まとめ

銅 (II) イオンは,パーキンソン病に関連するタンパク質であるアルファ-シヌクレインに強く結合します. この相互作用は,タンパク質のN端近くで発生し,位置50のヒスティジンを含まない.

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A Method to Study α-Synuclein Toxicity and Aggregation Using a Humanized Yeast Model08:24

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