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Updated: Jul 5, 2026

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
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IL-21とTGF-βは,ヒトのT(H) 17細胞の分化のために必要である

Li Yang1, David E Anderson, Clare Baecher-Allan

  • 1Division of Molecular Immunology, Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|May 13, 2008
PubMed
まとめ

成長因子-β (TGF-β) とIL-21の変換により,先天的なヒトのCD4 ((+)) T細胞がT ((H)) 17細胞に特異的に分化されます. これらの発見は,ヒトの自己免疫疾患におけるT(H) 17細胞の理解を進めている.

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