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Updated: Jul 5, 2026

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
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Constructing Cyclic Peptides Using an On-Tether Sulfonium Center

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バイサイクルペプチドのリボソーム合成は,2つの正交互の横鎖反応を介して行われます

Yusuke Sako1, Jumpei Morimoto, Hiroshi Murakami

  • 1Research Center for Advanced Science and Technology, The University of Tokyo, Komaba, Meguro, Tokyo 153-8904, Japan.

Journal of the American Chemical Society
|May 16, 2008
PubMed
まとめ

この研究は,再プログラムされた遺伝子コードを使用してバイサイクルペプチドを合成するための新しい細胞フリー方法を導入しています. この技術により,非タンパク質原性アミノ酸を正確に組み込み,均一なペプチド基板を作成することができます.

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