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Updated: Aug 3, 2026

Quantitation and Analysis of the Formation of HO-Endonuclease Stimulated Chromosomal Translocations by Single-Strand Annealing in Saccharomyces cerevisiae
09:40

Quantitation and Analysis of the Formation of HO-Endonuclease Stimulated Chromosomal Translocations by Single-Strand Annealing in Saccharomyces cerevisiae

Published on: September 23, 2011

トリプルヘリックス形成によって媒介される酵母ゲノムDNAの単一サイト酵素分裂

S A Strobel1, P B Dervan

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena 91125.

Nature
|March 14, 1991
PubMed
まとめ

この研究では,オリゴヌクレオチド誘導型トリプルヘリックス形成を用いた精密なDNA分裂のための新しい方法が紹介されています. この技術により,大型ゲノムDNAの標的切断が可能になり,染色体マッピングと遺伝子分離が容易になります.

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