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GPI Anchoring of Proteins in the ER Membrane
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16歳と17歳の16歳と17歳の全種全血献血に対する副作用
Anne F Eder1, Christopher D Hillyer, Beth A Dy
1Biomedical Services, Medical Office, National Headquarters, American Red Cross, 2025 E St NW, Washington, DC 20006, USA. edera@usa.redcross.org
JAMA
|May 22, 2008
まとめ
16~17歳のティーンエイジャーは,年配の献血者よりも多くの献血合併症を経験します. これは,若いドナーを保護し,将来の寄付を奨励するために,強化された安全対策の必要性を強調しています.
科学分野:
- 輸血医学とは
- 青少年の健康について
- 公衆衛生は公衆衛生である.
背景:
- 16歳と17歳の若者の献血は,アメリカ赤十字の全血収集の8%を占めています.
- 年齢の若さと初代ドナーの地位は,ドネーションに関連する有害事象のリスク要因として認識されています.
研究 の 目的:
- 16歳と17歳の全種全血献血献血者における有害反応の発生率を,年上の献血者と比較するために.
- 青少年献血者における献血者保持に対する安全性と影響を評価する.
主な方法:
- 2006年にアメリカ赤十字の9つのセンターで16歳と17歳のドナーに有害事象を記録した見通し研究.
- 標準化されたプロトコル,定義,および報告方法がデータ収集に使用されました.
- 分析は1万件あたりの全身 (シンコパル) 及びフレボトミー関連の合併症に焦点を当てた.
主要な成果:
- 副作用は16歳と17歳のドナーの10.7%で,18歳と19歳のドナーの8.3%と20歳以上のドナーの2.8%と比較して発生しました.
- 若い年齢 (OR,3.05),初めて献血 (OR,2.63),女性の性別 (OR,1.87) は合併症と有意に関連していました.
- 医学的に重要な傷害,特に昏睡に関連した転倒による傷害は,高齢のドナー (0.4/10,000) よりも16歳と17歳の若者 (5.9/10,000) でより頻繁でした.
結論:
- 十代の献血者 (16~17歳) は,献血関連の合併症や怪我の発生率が高くなります.
- 合併症を経験した16歳児では,リターン・ドネーション率の有意な減少が観察されました.
- 強化されたドナー安全プロトコルは,特に高校の献血で,若いドナーへの依存を考慮して,非常に重要です.
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