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Updated: Jul 5, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
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Published on: March 9, 2012

Rag GTPasesはラプターに結合し,mTORC1へのアミノ酸シグナル伝達を媒介する

Yasemin Sancak1, Timothy R Peterson, Yoav D Shaul

  • 1Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology (MIT), Nine Cambridge Center, Cambridge, MA 02142, USA.

Science (New York, N.Y.)
|May 24, 2008
PubMed
まとめ

Ragタンパク質は,アミノ酸への反応としてmTORC1経路を活性化するために不可欠です. これらのGTPasesはmTORC1の局所化を媒介し,細胞成長とがん経路に影響を与えます.

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