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Updated: Jul 5, 2026

Resin-Assisted Capture Coupled with Isobaric Tandem Mass Tag Labeling for Multiplexed Quantification of Protein Thiol Oxidation
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細胞およびミトコンドリアのチオレドキシンによる制御されたタンパク質デニトロシル化

Moran Benhar1, Michael T Forrester, Douglas T Hess

  • 1Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

Science (New York, N.Y.)
|May 24, 2008
PubMed
まとめ

チオレドキシン酵素は,重要な細胞シグナル伝達プロセスであるタンパク質デニトロシル化を調節する. この研究では,チオレドキシン-1とチオレドキシン-2が,細胞信号伝達とアポトーシスに影響を与えるカスパース-3の重要なデニトロシルアゼであると特定しています.

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