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Updated: Mar 20, 2026

Using En Face Immunofluorescence Staining to Observe Vascular Endothelial Cells Directly
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多剤耐性タンパク質-1は,オキシダティブストレス,内皮機能不全,および白血球C4輸出経由によるアテロゲネシスに影響します

Cornelius F H Mueller1, Kerstin Wassmann, Julian D Widder

  • 1Medizinische Klinik und Poliklinik II, Universitätsklinikum Bonn, Sigmund Freud Str 25, 53105 Bonn, Germany. cornelius.mueller@ukb.uni-bonn.de

Circulation
|May 29, 2008
PubMed
まとめ

多剤耐性タンパク質-1 (MRP1) と白血糖C4 (LTC4) は,血管細胞における酸化ストレスを増やすことで動脈硬化を促進します. MRP1またはLTC4受容体を阻害すると,プラーク形成が減り,血管機能が改善されます.

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