Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
Characteristics and Nomenclature of Copolymers01:24

Characteristics and Nomenclature of Copolymers

Copolymers are the products obtained from the polymerization of multiple monomer species. So, in a polymer chain itself, there can be multiple repeating units that come from different monomers. The process of synthesizing a polymer from different monomer species is called copolymerization. When two monomers are involved, the polymer is known as a bipolymer. Polymers with three and four monomers are termed terpolymers and quaterpolymers, respectively. Figure 1 depicts the copolymerization of...
Radical Chain-Growth Polymerization: Mechanism01:09

Radical Chain-Growth Polymerization: Mechanism

The radical chain-growth polymerization mechanism consists of three steps: initiation, propagation, and termination of polymerization. The polymerization initiates when a free radical generated from the radical initiator adds to the unsaturated bond in the monomer. The unpaired electron of the free radical and one π electron in the unsaturated bond creates a σ bond between the free radical and the monomer. As a result, the other π electron in the unsaturated bond converts this species into the...
Cationic Chain-Growth Polymerization: Mechanism00:57

Cationic Chain-Growth Polymerization: Mechanism

The cationic polymerization mechanism consists of three steps: initiation, propagation, and termination. In the initiation step of the polymerization process, the π bond of a monomer gets protonated by the Lewis acid catalyst, which is formed from boron trifluoride and water. The protonation of the π bond generates a carbocation stabilized by the electron‐donating group. In the propagation step, the π bond of the second monomer acts as a nucleophile and attacks the generated carbocation,...
Step-Growth Polymerization: Overview01:03

Step-Growth Polymerization: Overview

Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
Many natural and synthetic polymers are produced by...
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Small molecule activators of the mitochondrial protease ClpP induce senescence in triple-negative breast cancer cells and sensitize cells to the Bcl-2 inhibitor venetoclax.

Cell death & disease·2026
Same author

Nuclear SUN2 coordinates endothelial cell-matrix interactions to regulate blood vessel homeostasis and barrier function.

bioRxiv : the preprint server for biology·2026
Same author

Quantitative analysis of fibroblast migration reveals migratory states characterized by force generation, cell shape and motion.

bioRxiv : the preprint server for biology·2026
Same author

Author Correction: Coronin 1C inhibits melanoma metastasis through regulation of MT1-MMP-containing extracellular vesicle secretion.

Scientific reports·2026
Same author

Optogenetic control of PLC-γ1 activity directs cell motility.

The Journal of cell biology·2026
Same author

TRIM9 switches the morphological phenotype of melanoma cells.

bioRxiv : the preprint server for biology·2026
Same journal

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions.

Cell·2026
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
関連記事をすべて見る

関連する実験動画

Updated: May 11, 2026

Polymer Microarrays for High Throughput Discovery of Biomaterials
13:37

Polymer Microarrays for High Throughput Discovery of Biomaterials

Published on: January 25, 2012

モノメアに従う.

James E Bear1

  • 1Lineberger Comprehensive Cancer Center and Department of Cell and Developmental Biology University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. bear@email.unc.edu

Cell
|May 31, 2008
PubMed
まとめ
この要約は機械生成です。

アクチンキャピングタンパク質は驚くべきことに,Arp2/3の核形成と分岐を促進することによって,フィラメントの成長を加速することによってではなく,細胞の運動性を促進します. これは,細胞運動の調節のための新しいメカニズムを明らかにします.

さらに関連する動画

Preparation and Friction Force Microscopy Measurements of Immiscible, Opposing Polymer Brushes
13:57

Preparation and Friction Force Microscopy Measurements of Immiscible, Opposing Polymer Brushes

Published on: December 24, 2014

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
10:53

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions

Published on: October 10, 2016

関連する実験動画

Last Updated: May 11, 2026

Polymer Microarrays for High Throughput Discovery of Biomaterials
13:37

Polymer Microarrays for High Throughput Discovery of Biomaterials

Published on: January 25, 2012

Preparation and Friction Force Microscopy Measurements of Immiscible, Opposing Polymer Brushes
13:57

Preparation and Friction Force Microscopy Measurements of Immiscible, Opposing Polymer Brushes

Published on: December 24, 2014

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
10:53

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions

Published on: October 10, 2016

科学分野:

  • 細胞生物学 細胞生物学
  • バイオフィジックス 生物物理学
  • 細胞骨格のダイナミクス

背景:

  • アクチン繊維は,細胞の構造と運動性に不可欠です.
  • キャピングタンパク質はアクチンフィラメントの長さを調節する.
  • カッピングタンパク質による細胞運動性のパラドックスな増加は,完全に理解されていませんでした.

研究 の 目的:

  • アクチン・フィラメント・キャピングが細胞の運動性を高めるメカニズムを調査する.
  • キャピングタンパク質がフィラメントの伸びや核化/枝分かれに影響するかどうかを判断する.

主な方法:

  • 再構成された in vitro 運動系を用いた.
  • 操作されたアクチンフィラメントでタンパク質濃度を制限する.
  • 測定されたアクチン核化,枝分かれ,伸び率.

主要な成果:

  • フィラメントのキャピングは,Arp2/3ベースの核化を著しく増加させました.
  • フィラメントキャピングはアクチン分岐率を高めました.
  • カップリングは,フィラメントの伸び率を上昇させなかった.

結論:

  • アクチン・フィラメント・キャピングは,Arp2/3複合体の媒介によるde novoフィラメント形成を刺激することによって,細胞の運動性を促進する.
  • 主要なメカニズムは,核の強化と枝分かれであり,伸びの増大ではありません.
  • この発見は,細胞運動におけるアクチンダイナミクスの理解を修正するものである.