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Updated: Jul 4, 2026

Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation
09:16

Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation

Published on: June 26, 2018

膀に結合したアルファ-シヌクレインのヘリクスの対平行配列

Malte Drescher1, Gertjan Veldhuis, Bart D van Rooijen

  • 1Department of Molecular Physics, Leiden University, P.O. Box 9504, 2300 RA Leiden, The Netherlands.

Journal of the American Chemical Society
|June 3, 2008
PubMed
まとめ

パーキンソン病のタンパク質アルファ-シヌクレイン (alphaS) は,膜に結合するとき,曲げられた反パラレルヘリックス構造を採用します. この発見は,膜相互作用に関連したタンパク質の構成を明確にします.

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Millisecond Hydrogen/Deuterium-Exchange Mass Spectrometry for the Study of Alpha-Synuclein Structural Dynamics Under Physiological Conditions08:40

Millisecond Hydrogen/Deuterium-Exchange Mass Spectrometry for the Study of Alpha-Synuclein Structural Dynamics Under Physiological Conditions

Published on: June 23, 2022

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