肥満,行動的なライフスタイル要因,急性冠動脈事件のリスク
Majken K Jensen1, Stephanie E Chiuve, Eric B Rimm
1Department of Clinical Epidemiology, Aarhus University Hospital, Sdr Skovvej 15, DK-9100 Aalborg, Denmark. mkj@dce.au.dk
Circulation
|June 11, 2008
まとめ
肥満は急性冠動脈症候群 (ACS) のリスクを高めますが,身体活動や禁煙などの健康的なライフスタイルの選択はこれを軽減することができます. 肥満の個人でさえ,より健康的な習慣から恩恵を受けます.
科学分野:
- 心臓病学 心臓病学
- 公衆衛生は公衆衛生である.
- エピデミオロジー エピデミオロジー
背景:
- 肥満,身体活動,急性冠動脈症候群 (ACS) のリスクとの相互作用は議論されている.
- 他の変更可能なライフスタイル要因がACSリスクに対する肥満の影響をどのように影響するかに関するデータは限られている.
研究 の 目的:
- 急性冠動脈症候群 (ACS) のリスクに対する肥満とライフスタイル要因 (身体活動,喫煙,ダイエット) の組み合わせた影響を調査する.
主な方法:
- デンマークのダイエット,がん,健康研究からの54,783人の成年者 (50-64歳) の前向きなコホート研究.
- 追跡期間は平均7.7年,急性冠動脈症候群 (ACS) の症例を記録した.
- ボディマス指数 (BMI),身体活動,喫煙,食事パターンに対する多変数調整.
主要な成果:
- BMIの1単位増加ごとに,ACSのリスクが5% (女性) と7% (男性) 高いと相関していた.
- 体重過多と肥満は,身体活動,喫煙状態,または食事の遵守に関係なく,ACSのリスクが上昇しました.
- 週に1〜3時間半の身体活動をする肥満者は,座っている肥満者よりもACSのリスクが低い.
- 肥満の非喫煙者は,肥満の喫煙者よりもACSのリスクが低かった.
- 健康的な食事の遵守はACSのリスクを低下させたが,最も健康的な食事と,より健康的でない食事の肥満者の間ではリスクは似ていた.
結論:
- 肥満は,様々なライフスタイルのプロフィールにおいて,急性冠動脈症候群 (ACS) のリスクを独立して増加させる.
- 身体活動や禁煙を含む健康的な生活習慣の遵守は,肥満者の場合でも,ACSのリスクを低下させる.
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