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Updated: Jul 4, 2026

06:09
Rapid Isolation of Single Cells from Mouse and Human Teeth
Published on: October 28, 2021
歯磨きと歯抜きに関連した細菌血症
Peter B Lockhart1, Michael T Brennan, Howell C Sasser
1Department of Oral Medicine, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232-2861, USA. Peter.Lockhart@carolinashealthcare.org
Circulation
|June 11, 2008
まとめ
歯磨きは,アモキシチリン予防の有効性にもかかわらず,単一歯の抽出よりも感染症性内心炎 (IE) の細菌性のリスクが大きい可能性があります. 日々の口腔衛生の実践は,IE予防戦略を慎重に検討することを保証します.
科学分野:
- 口腔微生物学 口腔微生物学
- 感染症 感染症は感染症です.
- 心臓病学 心臓病学
背景:
- 現在の感染症性内心炎 (IE) 予防ガイドラインでは,歯科の手続きによるバクテレミアを考慮しています.
- 歯磨きは,口腔衛生の頻繁な活動であり,IEリスクに大きく寄与する可能性があります.
研究 の 目的:
- 歯磨きと単一歯の抽出の間の細菌血症の発生率,持続時間,性質,および大きさを比較するために.
- 単一歯抜きの手続きにおけるアモキシチリン予防の有効性を評価する.
主な方法:
- 290人の被験者を対象としたダブルブラインド・プラセボ対照試験です.
- ランダム化により,歯磨き,アモキシチリンによる抽出,またはプラセボによる抽出を行う.
- IEに関連するバクテリアを特定するために6つの時間点で採取された血液培養物.
主要な成果:
- IEに関連する細菌血症の累積発生率は23% (歯磨き),33% (抽出アモキシシリン),60% (抽出プラセボ) でした.
- 介入後のグループ間で,細菌血症の有意な差異が観察されました.
- アモキシシリンは陽性細菌培養を著しく減少させた (P<0.0001).
結論:
- 歯磨きは,単一歯の抽出と比較して,IEのリスクのある個人に,より大きなバクテリアの脅威をもたらす可能性があります.
- アモキシシリンは,歯抜きによるバクテリーミアの減少に有意な影響を示しています.
- よくある口腔衛生の実践は,IEの予防のために注意深く評価する必要があります.
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