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Updated: Jul 4, 2026

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
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Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine

Published on: June 13, 2022

キラルバッキーボウル,トリメチルスマンエンの非対称合成

Shuhei Higashibayashi1, Hidehiro Sakurai

  • 1Research Center for Molecular Scale Nanoscience, Institute for Molecular Science, Myodaiji, Okazaki 444-8787, Japan.

Journal of the American Chemical Society
|June 17, 2008
PubMed
まとめ

研究者らは,キラルバッキーボウル (C) -8,13,18-トリメチルスマンエンの最初の非対称合成を達成しました. このブレークスルーは,sp3センターのキラリティをボウルキラリティに変換し,分子設計の新たな道を開きます.

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Prochirality02:05

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The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...
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Chirality at Nitrogen, Phosphorus, and Sulfur

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