G

Jung Hee Park1, Patrick Scheerer, Klaus Peter Hofmann

  • 1Institut für Medizinische Physik und Biophysik (CC2), Charité-Universitätsmedizin Berlin, Charitéplatz 1, D-10117 Berlin, Germany.

Nature
|June 20, 2008
PubMed
まとめ

我々は,リガンドフリーオプシンの結晶構造を決定し,ロドプシンと比較して有意な構造変化を明らかにした. Gタンパク質結合受容体 (GPCR) 構造のこれらの変化は,網膜結合のための開口を作り出し,GPCRの活性化に関する洞察を提供します.

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