脳卒中発症の昼間変動のパターンの急激なシフトは,サマータイムへの移行とともに起こります
Christian Foerch1, Horst-Werner Korf, Helmuth Steinmetz
1Department of Neurology, Goethe University, Schleusenweg 2-16, 60528 Frankfurt am Main, Germany. foerch@em.uni-frankfurt.de
Circulation
|June 25, 2008
まとめ
デイライト・セービング・タイム (DST) 移行は,脳卒中発症時間を直ちにシフトさせ,朝の活動などの外的要因が毎日の脳卒中パターンに影響することを示しています. これは,迅速な内部日経時計の調整を主な原因として挑戦しています.
科学分野:
- 神経学 神経学とは
- クロノバイオロジー クロノバイオロジー
- 公衆衛生は公衆衛生である.
背景:
- 脳卒中の発症は昼間変動があり,朝にピークに達します.
- 身体活動などの内部生物リズムや外部要因が潜在的影響要因である.
- 日光節約時間 (DST) 移行は,外部時計の影響を研究するユニークな機会を提供します.
研究 の 目的:
- 外部時計のシフト,特にデイライト・セービング・タイム (DST) の移行が,脳卒中発症の昼間のパターンにどのように影響するか調査する.
- 脳卒中発生の毎日の変動における外部因子の役割を評価する.
主な方法:
- ドイツにおける潜在的脳卒中登録 (44,251人の患者,2000~2005年) の分析.
- 脳卒中の発生時間は,DST期間中に統一されたタイムラインに標準化されました.
- DST移行 (春と秋) 前のおよび後の脳卒中発症パターンの比較.
主要な成果:
- DSTの移行は,最初の1週間以内に脳卒中発症時間の即時のシフトを引き起こしました.
- -60分 (春) と+60分 (秋) のシフトが,脳卒中発症率のパーセンチルで観察されました.
- 重要な変化は,移行後の1日目と2日目の早い段階で明らかでした.
結論:
- 外部時計の変更は,DSTの移行のように,脳卒中発症のタイミングの即時シフトと直接関連しています.
- これは,目覚めに関連した外因的な要因が昼間の脳卒中変動に重要な役割を果たすという仮説を支持する.
- 人間の昼夜時計の急速な引き寄せは,これらの即時のシフトを説明する可能性は低い.
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