関連する実験動画

Updated: May 4, 2026

Pull-down of Calmodulin-binding Proteins
07:51

Pull-down of Calmodulin-binding Proteins

Published on: January 23, 2012

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カルモジュリンによるローカルおよびグローバルCa2+センシングのメカニズムは,Ca2+チャネルとの複合体によるものです

Michael R Tadross1, Ivy E Dick, David T Yue

  • 1Calcium Signals Laboratory, Departments of Biomedical Engineering and Neuroscience, The Johns Hopkins University School of Medicine, Ross Building, Room 713, 720 Rutland Avenue, Baltimore, MD 21205, USA.

Cell
|July 1, 2008
PubMed
まとめ

カルモジュリンは,局所的なカルシウム感知のためにそのC-ロブを使用し,グローバルな感知のためにN-ロブを使用します. グローバルなカルシウム感知は,迅速なカルシウム放出とチャネル親和の違いから生じ,複雑な解読機構を明らかにします.

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