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Updated: May 1, 2026

Isolation of Labile Multi-protein Complexes by in vivo Controlled Cellular Cross-Linking and Immuno-magnetic Affinity Chromatography
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ベータ1-アドレナジックGタンパク質結合受容体の構造

Tony Warne1, Maria J Serrano-Vega, Jillian G Baker

  • 1MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.

Nature
|July 3, 2008
PubMed
まとめ

シアノピンドロールに結合するβ(1) - アドレナージック受容体の結晶構造は,Gタンパク質結合受容体シグナル伝達のための重要な相互作用を明らかにします. これは,受容体活性化メカニズムと,トランスメブラン信号伝達経路のための潜在的な薬物開発の洞察を提供します.

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