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Updated: Sep 23, 2026

Induction of Acute Skeletal Muscle Regeneration by Cardiotoxin Injection
07:39

Induction of Acute Skeletal Muscle Regeneration by Cardiotoxin Injection

Published on: January 1, 2017

再結合キメリック毒素の細胞毒性作用は,迅速に増殖する血管の滑らかな筋肉細胞に作用する

S E Epstein1, C B Siegall, S Biro

  • 1Cardiology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892.

Circulation
|August 1, 1991
PubMed
まとめ

この研究では,表皮成長因子 (EGF) 受容体に結合することによって,迅速に増殖する滑らかな筋肉細胞 (SMC) を選択的に標的とし,殺すキメリック毒素であるTGFα-PE40を開発しました. このアプローチは,問題のあるSMCを排除することによって,レステノシスなどの状態を治療する可能性を示しています.

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