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Updated: May 20, 2026

Dissection of Hippocampal Dentate Gyrus from Adult Mouse
07:42

Dissection of Hippocampal Dentate Gyrus from Adult Mouse

Published on: November 18, 2009

哺乳類のメッセンジャーRNAに埋め込まれた不連続なハンマーヘッドリボ酵素

Monika Martick1, Lucas H Horan, Harry F Noller

  • 1Center for Molecular Biology of RNA, University of California, Santa Cruz, California 95064, USA. mmartick@yahoo.com

Nature
|July 11, 2008
PubMed
まとめ

遺伝子を調節するリボ酵素は,ネズミのClec2遺伝子3'未翻訳領域で発見されました. これらの不連続なハンマーヘッドリボ酵素は自己分裂し,タンパク質発現を減少させ,新しい転写後の遺伝子調節機構を明らかにします.

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Ribozymes02:47

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The term ribozyme is used for RNA that can act as an enzyme. Ribozymes are mainly found in selected viruses, bacteria, plant organelles, and lower eukaryotes. Ribozymes were first discovered in 1982 when Tom Cech’s laboratory observed Group I introns acting as enzymes. This was shortly followed by the discovery of another ribozyme, Ribonulcease P, by Sid Altman’s laboratory. Both Cech and Altman received the Nobel Prize in chemistry in 1989 for their work on ribozymes.
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