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Updated: Jul 3, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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Published on: June 15, 2011

最近の共通の祖先を追跡することによって,自閉症の位置と遺伝子を特定する

Eric M Morrow1, Seung-Yun Yoo, Steven W Flavell

  • 1Division of Genetics, Children's Hospital Boston and Harvard Medical School, Boston, MA 02115, USA.

Science (New York, N.Y.)
|July 16, 2008
PubMed
まとめ

この研究では,自閉症スペクトル障害の遺伝的原因を特定するために,家族におけるホモジゴシティマッピングを使用しました. PCDH10やDIA1のような重要な遺伝子が関与しており,神経活動における遺伝子発現の変化が一般的な自閉症メカニズムであることを示唆しています.

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