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Updated: Jul 3, 2026

A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products
09:04

A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products

Published on: September 9, 2016

バイオヤナギンAおよびその類似体の総合合成,改訂された構造,および生物学的評価

K C Nicolaou1, T Robert Wu, David Sarlah

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA. kcn@scripps.edu

Journal of the American Chemical Society
|July 24, 2008
PubMed
まとめ

研究者らはバイオヤナギンAと同類物を合成し,その構造を修正し,抗HIVと抗サイトカインの性質を確認した. ハイパーオラクトンCドメインは,バイオヤナギンAの鍵です.

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