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Updated: Jul 3, 2026

Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking
11:33

Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking

Published on: December 17, 2013

病原体タンパク質 EspF(U) は,真似と多価性を用いてアクチンポリメリゼーションをハイジャックする.

Nathan A Sallee1, Gonzalo M Rivera, John E Dueber

  • 1Graduate Program in Chemistry and Chemical Biology, University of California, San Francisco, 600 16th Street, San Francisco, California 94158, USA.

Nature
|July 25, 2008
PubMed
まとめ

エントロヘモラジックなEscherichia coliはEspF (U) タンパク質を使用して宿主細胞のアクチン足場形成を誘発します. このタンパク質は,CDC42ではなく,内部のN-WASP要素を独特に模倣して,細菌の結合のためのアクチンポリメリゼーションを活性化します.

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