成人における侵襲的なB群の estreptococcal疾患. 大都市アトランタの人口ベースの研究
B Schwartz1, A Schuchat, M J Oxtoby
1Meningitis and Special Pathogens Branch, Centers for Disease Control, Atlanta, GA 30333.
JAMA
|August 28, 1991
まとめ
グループB型ストレプトコッカス (GBS) 感染症は,成人の場合,32%の死亡率で深刻です. 糖尿病やがんを患っている大人は,著しく高いリスクに直面しており,予防戦略の必要性を強調しています.
科学分野:
- 感染症 感染症は感染症です.
- エピデミオロジー エピデミオロジー
- バクテリア学 バクテリア学
背景:
- グループB型ストレプトコッカス (GBS) は,主に新生児感染症で知られている重要な病原体です.
- 成人のGBS感染はあまり理解されていないが,深刻な結果につながる可能性があります.
研究 の 目的:
- 成人のGBS感染の発生率と臨床的症状を決定する.
- GBS感染のリスクが高い特定の成人の集団を特定する.
主な方法:
- 人口をベースにした遡及的監視研究が行われました.
- データは,1982年から1983年にかけての大都市アトランタの微生物学の記録と患者の医療チャートから収集されました.
主要な成果:
- 成人におけるGBSの年間発生率は10万人あたり2.4人であり,年齢とともに増加し,黒人個体ではより高い.
- 症例死亡率は32%で,皮膚/軟組織感染症と細菌血症を含む一般的なプレゼンテーションがあります.
- 糖尿病 (10.5倍のリスク増加) と癌 (16.4倍のリスク増加) が有る個人は,著しく感受性が高かった.
結論:
- GBSは,新生児と同様に,成人でも重篤な疾患を引き起こすため,ワクチン開発の必要性を強調しています.
- 成人のGBSの発生率と危険因子を理解することは,標的型予防の取り組みにとって極めて重要です.
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