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Updated: Aug 18, 2026

Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding
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グルココルチコイド受容体とDNAの相互作用の結晶分析

B F Luisi1, W X Xu, Z Otwinowski

  • 1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06511.

Nature
|August 8, 1991
PubMed
まとめ

グルココルチコイド受容体のDNA結合ドメインは,DNAを結合すると二元化します. DNAの距離は,ターゲット認識を決定的に決定し,グルココルチコイド受容体機能の特定のおよび非特定の相互作用に影響を与えます.

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