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Updated: May 3, 2026

A Rapid In Vivo Bioassay for Developmentally Active Enhancers
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モーターニューロン多様性と接続性に関するホックスのレパートリーは,単一の付属因子,FoxP1によってゲートされています

Jeremy S Dasen1, Alessandro De Camilli, Bin Wang

  • 1Smilow Neuroscience Program, Department of Physiology and Neuroscience, New York University School of Medicine, New York, NY 10016, USA. jeremy.dasen@nyumc.org

Cell
|July 30, 2008
PubMed
まとめ

フォークヘッドボックスタンパク質P1 (FoxP1) は,モーターニューロンのアイデンティティと接続性を調整します. FoxP1の喪失はホックス・ネットワークを混乱させ,ランダムなモーター・アクソン・ターゲティングを引き起こし,脊髄運動系を先祖の状態に戻します.

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