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Updated: Jul 3, 2026

Deacetylation Assays to Unravel the Interplay between Sirtuins (SIRT2) and Specific Protein-substrates
14:32

Deacetylation Assays to Unravel the Interplay between Sirtuins (SIRT2) and Specific Protein-substrates

Published on: February 27, 2016

NAD+依存型脱酸化酵素SIRT1は,CLOCK媒介のクロマチンの改造と昼夜制御を調節する

Yasukazu Nakahata1, Milota Kaluzova, Benedetto Grimaldi

  • 1Department of Pharmacology, University of California, Irvine, CA 92697, USA.

Cell
|July 30, 2008
PubMed
まとめ

昼間の時計タンパク質CLOCKはヒストンH3とBMAL1.1をアセチレートする. NAD (((+) 依存型脱酸化酵素SIRT1は,これらのタンパク質を脱酸化することによって昼夜リズムを調節し,重要な代謝センサーとして作用します.

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Rapid Analysis of Circadian Phenotypes in Arabidopsis Protoplasts Transfected with a Luminescent Clock Reporter07:42

Rapid Analysis of Circadian Phenotypes in Arabidopsis Protoplasts Transfected with a Luminescent Clock Reporter

Published on: September 17, 2016

A Filtration-based Method of Preparing High-quality Nuclei from Cross-linked Skeletal Muscle for Chromatin Immunoprecipitation10:04

A Filtration-based Method of Preparing High-quality Nuclei from Cross-linked Skeletal Muscle for Chromatin Immunoprecipitation

Published on: July 6, 2017

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