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Updated: Feb 23, 2026

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
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イカッパBキナーゼ2によるSNAP-23のリン酸化は,マスト細胞のデグラヌレーションを調節する

Kotaro Suzuki1, Inder M Verma

  • 1Laboratory of Genetics, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Cell
|August 12, 2008
PubMed
まとめ

マスト細胞のイカッパBキナーゼ (IKK) 2は,アレルギー反応に不可欠です. 直接SNAP-23をリン酸化し,NF-kBとは無関係にIgE媒介のデグラヌレーションとアナフィラキシーを誘導する.

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