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サーファクチン合成酵素の外部チオエステラーゼの選択性の構造的基礎

Alexander Koglin1, Frank Löhr, Frank Bernhard

  • 1Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance and Cluster of Excellence Macromolecular Complexes (CEF), J.W.-Goethe University, 60438 Frankfurt am Main, Germany.

Nature
|August 16, 2008
PubMed
まとめ

II型チオエステラーゼ (TEII) は,非リボソームペプチドおよびポリケチド合成酵素の重要な修復酵素である. 構造分析により,TEII酵素がどのように機能的なコファクターを再生し,タイプIチオエステラゼ (TEI) と区別するかを明らかにした.

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