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Updated: Jul 2, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
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Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach

Published on: June 10, 2021

クロロフーシン,その7つの染色体ダイアステロエーマー,および主要な部分構造の総合成

Ryan C Clark1, Sang Yeul Lee, Dale L Boger

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|August 21, 2008
PubMed
まとめ

p53-MDM2複合体の形成の天然阻害体であるクロロフーシンの全合成が達成されました. この研究では,その複雑な染色体の絶対的立体化学を割り当て,相対的立体化学を再割り当てました.

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