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Updated: Jul 2, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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フォスラクトマイシンのcis-Delta ((2,3) - 二重結合は,PKS後の裁縫酵素によって生成されます

Nadaraj Palaniappan1, Mamoun M Alhamadsheh, Kevin A Reynolds

  • 1Department of Chemistry, Portland State University, Portland, OR 97297, USA.

Journal of the American Chemical Society
|August 22, 2008
PubMed
まとめ

抗真菌フォスラクトマイシン (PLM) は,異例のシス二重結合を有しています. 新しい遺伝子であるplmT2は,cis Delta2,3アルケンの形成に不可欠であり,ポリケチド生物合成に関する新しい洞察を明らかにしています.

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