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Updated: Jul 2, 2026

Purification of Ubiquitinated p53 Proteins from Mammalian Cells
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PTENのデウビキキチニル化と局所化は,HAUSP-PMLネットワークによって規制されています

Min Sup Song1, Leonardo Salmena, Arkaitz Carracedo

  • 1Cancer Genetics Program, Beth Israel Deaconess Cancer Center and Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.

Nature
|August 22, 2008
PubMed
まとめ

核PTEN (染色体10で削除されたホモログのフォスファタゼとテンシン) の排除は癌を誘発する. 新しいPML-DAXX-HAUSPネットワークは,PTENデウビキキチニレーションと核エントリーを制御し,がんの進行に関する洞察を提供します.

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